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Nocardia farcinica

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Nocardia farcinica is a species of bacteria, once thought to be associated with farcy, and a member of the genus Nocardia. This species is very similar in phenotype to Nocardia asteroides, to the degree that some isolates of N. asteroides were later found to be Nocardia farcinica.[3]

Pathogenicity

N. farcinica may be a causative agent of nocardiosis[4] or of secondary infections in immunocompromised patients.[5] Strains of this species have been isolated from human brain abscesses.[6]

Genome

N. farcinica contains a 6 million base pair genome with an average GC content of 70.8%. A sequenced strain, IFM 10152, is also known to contain two plasmids, pNF1 pNF2. The chromosome encodes 5,674 potential protein-coding open reading frames. This genome may have undergone numerous gene duplication events as a result of adapting to new environments.[7]

References

  1. ^ Parte, A.C. "Nocardia". LPSN.
  2. ^ Kämpfer P, Dott W, Kroppendstedt RM. (1990). "Numerical classification and identification of some nocardioform bacteria". The Journal of General and Applied Microbiology. 36 (5): 309–331. doi:10.2323/jgam.36.309.
  3. ^ Wallace RJ Jr.; Tsukamura, M; Brown, BA; Brown, J; Steingrube, VA; Zhang, YS; Nash, DR (December 1990). "Cefotaxime-resistant Nocardia asteroides strains are isolates of the controversial species Nocardia farcinica". Journal of Clinical Microbiology. 28 (12): 2726–32. doi:10.1128/JCM.28.12.2726-2732.1990. PMC 268263. PMID 2280003.
  4. ^ Holm, P (July 1975). "Seven cases of human nocardiosis caused by Nocardia farcinica". Sabouraudia. 13 (2): 161–9. doi:10.1080/00362177585190301. PMID 1162538.
  5. ^ Torres, O. H.; Domingo, P.; Pericas, R.; Boiron, P.; Montiel, J. A.; Vázquez, G. (3 April 2000). "Infection Caused by Nocardia farcinica : Case Report and Review". European Journal of Clinical Microbiology & Infectious Diseases. 19 (3): 205–212. doi:10.1007/s100960050460. PMID 10795594. S2CID 6487051.
  6. ^ Malincarne, Lisa; Marroni, Massimo; Farina, Claudio; Camanni, Guido; Valente, Marina; Belfiori, Barbara; Fiorucci, Stefano; Floridi, Piero; Cardaccia, Angela; Stagni, Giuliano (1 May 2002). "Primary brain abscess with Nocardia farcinica in an immunocompetent patient". Clinical Neurology and Neurosurgery. 104 (2): 132–135. doi:10.1016/S0303-8467(01)00201-3. PMID 11932043. S2CID 35619104.
  7. ^ Ishikawa, J; Yamashita, A; Mikami, Y; Hoshino, Y; Kurita, H; Hotta, K; Shiba, T; Hattori, M (Oct 12, 2004). "The complete genomic sequence of Nocardia farcinica IFM 10152". Proceedings of the National Academy of Sciences of the United States of America. 101 (41): 14925–30. doi:10.1073/pnas.0406410101. PMC 522048. PMID 15466710.
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Nocardia farcinica: Brief Summary

provided by wikipedia EN

Nocardia farcinica is a species of bacteria, once thought to be associated with farcy, and a member of the genus Nocardia. This species is very similar in phenotype to Nocardia asteroides, to the degree that some isolates of N. asteroides were later found to be Nocardia farcinica.

license
cc-by-sa-3.0
copyright
Wikipedia authors and editors
original
visit source
partner site
wikipedia EN