Mononegaviruses

This negatively-stained transmission electron micrograph (TEM) revealed the presence of numerous negative-sense, single-stranded RNA ((-) ssRNA) Flanders virus virions. Note the bullet-like shape of these virions, which are very similar to other Rhabdoviruses, i.e., see PHIL 1876 depicting a TEM revealing the bullet-shaped rabies virus virions.Created: 1975

This negatively-stained transmission electron micrograph (TEM) revealed the presence of numerous bovine ephemeral fever virus virions, which are members of the Rhabdoviridae family of viruses, and the genus Ephemerovirus, infecting animals as well as plants.Created: 1975

This negatively-stained transmission electron micrograph (TEM) revealed the presence of two Piry virus virions. Note the bullet-like shape of the small 155nm x 162nm virions. Normally, under electron microscopic examination, the virions are observed as being discoidal or spheroidal in shape, and only rarely as bullet-shaped, as was the case here.Created: 1975

This negatively-stained transmission electron micrograph (TEM) revealed the presence of numerous Piry virus virions, many of which could be seen as they were budding from the host cell, thereby, becoming free to migrate throughout the host’s system. Note the bullet-like shape of the small 155nm x 162nm virions, as they’re freed from the host cell. Normally, under electron microscopic examination, the virions are observed as being discoidal or spheroidal in shape, and only rarely as bullet-shaped, as was the case here.Created: 1975

This transmission electron micrograph (TEM) revealed some of the internal cross-sectional structural morphology of a rabies virion (arrow) in this central nervous system tissue specimen. The virion is adjacent to a Negri body, which is pathognomonic in the positive diagnosis for Rabies. The virus infects the central nervous system, causing encephalopathy and ultimately death. Rabies virus belongs to the order Mononegavirales, viruses with a nonsegmented, negative-sense single-stranded RNA ((-) ssRNA) genomes. Within this group, viruses with a distinct "bullet" shape are classified in the Rhabdoviridae family, which includes at least three genera of animal viruses, Lyssavirus, Ephemerovirus, and Vesiculovirus. The genus Lyssavirus includes rabies virus, Lagos bat, Mokola virus, Duvenhage virus, European bat virus 1 & 2 and Australian bat virus.Created: 1975

This transmission electron micrograph (TEM) revealed some of the nucleocapsid morphologic features displayed by the human parainfluenza virus Type-4a (HPIV-4), a member of the Paramyxoviridae family. These viruses possess a genome consisting of negative-sense single-stranded RNA ((-) ssRNA).Each of the four HPIVs has different clinical and epidemiologic features. The most distinctive clinical feature of HPIV-1 and HPIV-2 is croup (i.e., laryngotracheobronchitis); HPIV-1 is the leading cause of croup in children, whereas HPIV-2 is less frequently detected. Both HPIV-1 and -2 can cause other upper and lower respiratory tract illnesses. HPIV-3 is more often associated with bronchiolitis and pneumonia. HPIV-4 is infrequently detected, possibly because it is less likely to cause severe disease. The incubation period for HPIVs is generally from 1 to 7 days.Created: 1975

This transmission electron micrograph (TEM) revealed the presence of the human parainfluenza type 4A virus (HPIV-4A), which like the mumps virus, is also a Paramyxoviridae family member, and a member of the genus, Rubulavirus.Created: 1975

This transmission electron micrograph (TEM) revealed the presence of the human parainfluenza type 4A virus (HPIV-4A), which like the mumps virus, is also a Paramyxoviridae family member, and a member of the genus, Rubulavirus.Created: 1975

This transmission electron micrograph (TEM) revealed the presence of numerous paramyxovirus virions, which in this instance, were responsible for a case of the mumps. Paramyxoviruses are members of the family, Paramyxoviridae, and those that cause mumps in humans belong to the genus, Rubulavirus. The virus itself can present itself in a number of morphologic shapes, including spherical, and stand-like, or filamentous, ranging from 150nm to 200nm in diameter, and 1000nm to 10000nm in length. At its core lies a non-segmented, negative-sense RNA genome.Created: 1975

This transmission electron micrograph (TEM) revealed the presence of numerous paramyxovirus virions, which in this instance, were responsible for a case of the mumps. Paramyxoviruses are members of the family, Paramyxoviridae, and those that cause mumps in humans belong to the genus, Rubulavirus. The virus itself can present itself in a number of morphologic shapes, including spherical, and stand-like, or filamentous, ranging from 150nm to 200nm in diameter, and 1000nm to 10000nm in length. At its core lies a non-segmented, negative-sense RNA genome.Created: 1975

Under a highly magnified view of 168,000x this transmission electron micrographic (TEM) image revealed ultrastructural details of a Nipah virus nucleocapsid, a virus which was named for the location in Malaysia where it was first isolated.Created: 1999