Caliciviridae

This transmission electron micrograph (TEM) revealed some of the ultrastructural morphology displayed by norovirus virions, or virus particles.Noroviruses belong to the genus Norovirus, and the family Caliciviridae. They are a group of related, single-stranded RNA, nonenveloped viruses that cause acute gastroenteritis in humans. Norovirus was recently approved as the official genus name for the group of viruses provisionally described as Norwalk-like viruses (NLV). See PHIL 10708 for a colorized version of this image.Created:

This transmission electron micrograph (TEM) revealed some of the ultrastructural morphology displayed by norovirus virions, or virus particles.Noroviruses belong to the genus Norovirus, and the family Caliciviridae. They are a group of related, single-stranded RNA, nonenveloped viruses that cause acute gastroenteritis in humans. Norovirus was recently approved as the official genus name for the group of viruses provisionally described as Norwalk-like viruses (NLV). See PHIL 10706 for a colorized version of this image.Created:

Description: English: Schematic representations of typical calicivirus genome organizations. (A–D) Genomic full-length RNAs of about 7.5 kb in size contain either two ORFs (in viruses of the genera Lagovirus, Nebovirus, and Sapovirus) or three ORFs (Norovirus and Vesivirus), except for the genomic RNA of Murine norovirus (MNV; genus Norovirus) that may contain an additional ORF (encoding the VF1 protein). (E) All caliciviruses except MNV and vesiviruses have subgenomic RNAs of about 2.1 kb in size with two ORFs that encode the main structural proteins, VP1 and VP2; the subgenomic RNA of MNV includes three ORFs (similar to the corresponding genomic RNA) and the subgenomic RNA of vesiviruses encodes – apart from proteins VP1 and VP2 – a small leader of the capsid protein (LC). Colored boxes represent coding sequences that are flanked by untranslated leader and trailer sequences (shown as lines). Hexagons represent VPg proteins that are covalently bound to the 5′ end of all genomic and subgenomic RNAs; An represents the poly(A) tail at the 3′ end of all genomic and subgenomic RNAs. Date: 6 June 2019. Source: https://www.frontiersin.org/articles/10.3389/fmicb.2019.01280/full. Author: Elena Smertina, Nadya Urakova, Tanja Strive, and Michael Frese.

Description: English: Domains, motifs, and homomorphs of a typical calicivirus RdRp. (A) Representation of a slightly cupped right hand resembling an RdRp with the position of motifs A to G on fingers, palm, and thumb. (B–D) Ribbon diagrams of the RHDV RdRp (PDB ID: 1KHW); (B) fingers, palm, and thumb domains colored blue, red, and green, respectively, and the N-terminal domain colored magenta; (C) structurally conserved homomorphs (hmA to hmH); and (D) functional motifs A to G (the positions of homomorphs and corresponding motifs are indicated by the same color). Ribbon diagrams were generated using Discovery Studio (Dassault Systèmes BIOVIA, Discovery Studio Visualizer v17.2.0, San Diego: Dassault Systèmes, 2016). Date: 6 June 2019. Source: https://www.frontiersin.org/articles/10.3389/fmicb.2019.01280/full. Author: Elena Smertina, Nadya Urakova, Tanja Strive, and Michael Frese.

Description: English: Chipotle Mexican Grill restaurant on Beacon Street in Cleveland Circle, Brighton. The restaurant was closed on December 3, 2015 after 140 people were sickened by a norovirus after eating there. Date: 16 December 2015. Source: Own work. Author: Pi.1415926535. Camera location42° 20′ 10.49″ N, 71° 08′ 57.74″ W View all coordinates using: OpenStreetMap 42.336247; -71.149372.

Description: English: Thirteen noroviruses: an electron micrograph. Magnification approximately 200 times. Date: 10 August 2017. Source: Own work. Author: Dr Graham Beards.

Description: English: Pronunciation recording of German noun "Norovirus", IPA: /ˈnoːʁoˌviːʁʊs/. Male voice, recorded by native German speaker from Berlin, Germany. Deutsch: Aussprachebeispiel des deutschen Substantivs "Norovirus", IPA: /ˈnoːʁoˌviːʁʊs/. Männliche Stimme, aufgenommen von deutschem Muttersprachler aus Berlin, Deutschland. Date: 18 July 2020. Source: Own work, recorded with Røde NT-USB and Audacity, converted with SoX (Sound eXchange audio editing software). Author: Jeuwre.

Description: Nederlands: Text reads: STOP. Afdeling niet betreden i.v.m. mogelijk NORO virus. Date: 24 November 2019, 16:36:19. Source: Own work. Author: Vysotsky.

Summary.mw-parser-output table.commons-file-information-table,.mw-parser-output.fileinfotpl-type-information{border:1px solid #a2a9b1;background-color:#f8f9fa;padding:5px;font-size:95%;border-spacing:2px;box-sizing:border-box;margin:0;width:100%}.mw-parser-output table.commons-file-information-table>tbody>tr,.mw-parser-output.fileinfotpl-type-information>tbody>tr{vertical-align:top}.mw-parser-output table.commons-file-information-table>tbody>tr>td,.mw-parser-output table.commons-file-information-table>tbody>tr>th,.mw-parser-output.fileinfotpl-type-information>tbody>tr>td,.mw-parser-output.fileinfotpl-type-information>tbody>tr>th{padding:4px}.mw-parser-output.fileinfo-paramfield{background:#ccf;text-align:right;padding-right:0.4em;width:15%;font-weight:bold}.mw-parser-output.commons-file-information-table+table.commons-file-information-table,.mw-parser-output.commons-file-information-table+div.commons-file-information-table>table{border-top:0;padding-top:0;margin-top:-8px}@media only screen and (max-width:719px){.mw-parser-output table.commons-file-information-table,.mw-parser-output.commons-file-information-table.fileinfotpl-type-information{border-spacing:0;padding:0;word-break:break-word;width:100%!important}.mw-parser-output.commons-file-information-table>tbody,.mw-parser-output.fileinfotpl-type-information>tbody{display:block}.mw-parser-output.commons-file-information-table>tbody>tr>td,.mw-parser-output.commons-file-information-table>tbody>tr>th,.mw-parser-output.fileinfotpl-type-information>tbody>tr>td,.mw-parser-output.fileinfotpl-type-information>tbody>tr>th{padding:0.2em 0.4em;text-align:left;text-align:start}.mw-parser-output.commons-file-information-table>tbody>tr,.mw-parser-output.fileinfotpl-type-information>tbody>tr{display:flex;flex-direction:column}.mw-parser-output.commons-file-information-table+table.commons-file-information-table,.mw-parser-output.commons-file-information-table+div.commons-file-information-table>table{margin-top:-1px}.mw-parser-output.fileinfo-paramfield{box-sizing:border-box;flex:1 0 100%;width:100%}} Description: 3D print of Norwalk virus, a type of norovirus. Noroviruses are the most common cause of acute gastroenteritis (infection of the stomach and intestines) in the United States. For more information, visit the NIH 3D Print Exchange at 3dprint.nih.gov. Credit: NIH. Date: 25 July 2013, 16:28. Source: Norwalk Virus. Author: NIAID.

Description: English: X-ray crystallographic structure of the Norwalk virus capsid. Date: 19 April 2001. Source: http://www.rcsb.org/pdb/explore/explore.do?structureId=1IHM. Author: Prasad, B.V., Hardy, M.E., Dokland, T., Bella, J., Rossmann, M.G., Estes, M.K. Permission (Reusing this file): http://www.pdb.org/pdb/static.do?p=general_information/about_pdb/policies_references.html.

Description: English: Mr. Norwalk, a model of the Norwalk virus, stands ready to attack. His brown color is indicative of the acute gastroenteritis that he will cause his host, while his puffy and cup puffy like hair exemplifies the structure of his VP1 proteins on his surface. Date: 19 November 2014, 15:53:09. Source: Own work. Author: Mtm3123.

Description: English: Rabbit Hemorrhagic Disease Virus (RHDV) capsid EMD-1933. Date: 4 December 2013, 19:45:12. Source: Own work. Author: A2-33.

Summary This electron micrograph reveals the morphologic traits exhibited by the feline calicivirus (FCV), a Caliciviridae family member. Feline calicivirus virions average 35nm - 40nm in diameter, and exhibit cup-like surface depressions, which sometimes manifest as a "Star of David" array. The feline symptoms include upper respiratory symptoms with oral ulcerations, and pneumonitis. Source: Center for Disease Contol Public Health Image Library Image #198. Licensing[edit] Public domainPublic domainfalsefalse. : This image is a work of the Centers for Disease Control and Prevention, part of the United States Department of Health and Human Services, taken or made as part of an employee's official duties. As a work of the U.S. federal government, the image is in the public domain. čeština | Deutsch | English | español | eesti | suomi | français | italiano | македонски | Nederlands | polski | português | slovenščina | українська | 中文 | 中文（简体）‎ | 中文（繁體）‎ | +/− :.

Description: English: Adult rabbit (Oryctolagus cuniculus) with jaundice. Yellowing of the mucous membranes and sclera is visible. Date: 14 August 2019, 15:27:27. Source: Own work. Author: Rabbit Vet.