Description: English: The arginase inhibitor BEC prevents larval immobilization during challenge infection in vivo. C57BL/6 mice were treated with S-(2-boronoethyl)-L-cysteine (BEC) (0.2%, 100 µl by oral gavage) during challenge Hp infection. Mice were sacrificed on day 4 p.i. and small intestines were removed. Pieces of the upper duodenum were carefully covered with cover slips and time lapse-movies were immediately recorded with an Olympus AX70 microscope. Movies were processed using iMovie software. Representative examples are shown. Date: November 2013. Source: Movie S5 from Esser-von Bieren J, Mosconi I, Guiet R, Piersgilli A, Volpe B, Chen F, Gause W, Seitz A, Verbeek J, Harris N (2013). "
Antibodies Trap Tissue Migrating Helminth Larvae and Prevent Tissue Damage by Driving IL-4R?-Independent Alternative Differentiation of Macrophages". PLOS Pathogens.
DOI:
10.1371/journal.ppat.1003771.
PMID 24244174.
PMC:
3828184. Author: Esser-von Bieren J, Mosconi I, Guiet R, Piersgilli A, Volpe B, Chen F, Gause W, Seitz A, Verbeek J, Harris N. Permission (
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