1-s2.0-S0166354209005385-gr10

Description:

Description: English: Overview of the flavivirus RdRp structure based on WNV NS5Pol (Malet et al., 2007) as an example; a “Front” view is presented here in ribbon representation. Fingers, palm and thumb subdomains are colored in blue, green and red, respectively. The ssRNA template entry and the dsRNA exit are shown by black arrows. A dotted arrow points to the NTP entry tunnel at the back of the RdRp. Motifs A, C, E, F, the G-loop and the priming loop are colored in orange, yellow, grey, magenta, cyan and purple, respectively. The Asp residues of catalytic motifs A and C (Asp-533, Asp-663 and Asp-664) are represented as stick models. N-ter and C-ter indicate the termini of the RdRp domain. Date: 1 August 2010. Source: https://www.sciencedirect.com/science/article/pii/S0166354209005385. Author: Michela Bollati, Karin Alvarez, René Assenberg, Cécile Baronti, Bruno Canard, Shelley Cook, Bruno Coutard, Etienne Decroly, Xavier de Lamballerie, Ernest A. Gould, Gilda Grard, Jonathan M. Grimes, Rolf Hilgenfeld, Anna M. Jansson, Hélène Malet, Erika J. Mancini, Eloise Mastrangelo, Andrea Mattevi, Mario Milani, Grégory Moureau, Johan Neyts, Raymond J. Owens, Jingshan Ren, Barbara Selisko, Silvia Speroni, Holger Steuber, David I. Stuart, Torsten Unge, Martino Bolognesi.